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What is Zyn and what are oral nicotine pouches?

As youth e-cigarette use remains a public health concern with 1.63 million middle and high school students reporting e-cigarette use in 2024, a different type of flavored nicotine product is gaining popularity: oral nicotine pouches.

Oral nicotine pouches are small white pouches, containing nicotine powder and flavorings, that are inserted into the mouth. The pouches are sometimes referred to as a "lip pillow" or "upper decky" because of where they are placed between the lip and gum, often under the upper lip. Oral nicotine pouches are used similarly to snus – an oral pouch containing shredded tobacco leaf – but unlike snus, they contain a nicotine powder instead of tobacco leaf and are therefore not classified as smokeless tobacco products. Nicotine pouches contain nicotine which is harmful to young people in any form.

Oral nicotine pouches include brands such as Zyn, On! and Velo. Oral nicotine pouches have gained popularity in recent years, and are now the second most commonly used tobacco product among middle and high school students, following e-cigarettes. 

Overall sales of nicotine pouch products increased from 126.06 million units from August to December 2019 to 808.14 million units from January to March 2022. During this period, sales of nicotine pouch products containing a higher concentration of nicotine (8 mg) increased more rapidly than products with lower nicotine concentrations (e.g., 4 mg and 6 mg). Most recently, the total monthly nicotine pouch sales increased by 207% between January 2023 and April 2025, from $145.5 million to $446.8 million

Advertisements for oral nicotine pouches highlight flavors and emphasize the “freedom” of using nicotine pouches anywhere, according to research co-authored by Truth Initiative. Leading nicotine pouch brands spent nearly $25 million on ads between January 2019 and September 2021.   

Ongoing data on oral nicotine pouch use, especially among young people, are needed. As more information emerges, here are some important things to know about these products. 

Zyn and Zyn Pouches

Who uses oral nicotine pouches?

Nicotine pouches are gaining popularity among teens and young adults, especially in rural areas and among White non-Hispanic youth. 

Youth and young adult use:  

Adult use:  

Dual use of oral nicotine pouches and e-cigarettes:  

Nicotine addiction continues to pose a serious public health risk, especially for young people. Nicotine pouches share multiple characteristics with e-cigarettes that have been shown to lead to significant youth usage, including high concentrations of nicotine, youth-appealing flavors, a significant presence on social media, and they are easy to conceal. It is essential that these highly addictive products are marketed responsibly and do not contribute to youth tobacco initiation.  

How much nicotine is in oral nicotine pouches?

How much nicotine is in Zyn?

Nicotine concentrations differ across oral nicotine pouch brands. For example, in the United States Zyn is sold in 3 and 6 mg, Velo is sold in 2, 4, and 7 mg, and On! is sold in 1.5, 2, 3.5, 4, and 8 mg, according to each brand’s website. Altria’s new On! nicotine pouch product, called On! Plus, offers nicotine strengths of 6, 9, and 12mg

What flavors do nicotine pouches come in?

What flavors does Zyn come in?

Oral nicotine pouches come in an array of youth-friendly flavors, including fruit, mint, and other flavors.

As of April 2025, mint flavors account for 62.1% of sales, while other flavors (e.g. fruits, candy, drinks) make up 23.2%, and smooth/original flavors at 10.6%

The availability of sweet, fruity, and candy-like flavors is troubling because, as pod-based e-cigarettes like JUUL face federal flavor restrictions in response to high rates of youth vaping, young people may switch to other nicotine products that still offer flavors. For example, disposable e-cigarettes, which were exempted from the partial flavor restrictions FDA enacted in January 2020, have skyrocketed in popularity. Sales of menthol-flavored e-cigarettes, which were also exempted, experienced a drastic, immediate rise in sales with an increase of almost $60 million and its market share more than doubled.

Flavors play a significant role in drawing youth to tobacco products – 87.6% of young e-cigarette users reported using a flavored product in 2024.

How are oral nicotine products regulated?

Is Zyn regulated?

Oral nicotine products are currently not regulated as tightly as other tobacco products. The FDA places some regulations on these products, including requirements that manufacturers submit certain information to the agency, use nicotine warning labels, and comply with some basic marketing restrictions. As of 2025, Zyn products are the only oral nicotine pouch products that have been authorized by the FDA. 

On January 16, 2025, the FDA announced the authorization of 20 flavored Zyn products, including Zyn Chill and Zyn Smooth. The decision was made after the FDA determined that the potential benefit of oral nicotine products for adults who smoke cigarettes and/or use other smokeless tobacco products outweighs the potential risks, including to youth. 

To reduce the risk of youth exposure, the FDA imposed stringent marketing restrictions for digital, TV, and radio advertisements, including measures to ensure ads are carefully targeted to adults ages 21 and older and requirements for the demographics reached by the ads to be tracked and measured by the manufacturer. The FDA may suspend or withdraw authorization if it determines the products are no longer appropriate for public health, or if there is a notable increase in youth initiation. 

In response to the proliferation of oral nicotine products on the market that lack FDA approval, Truth Initiative joined 5 leading public health and medical organizations to urge the FDA to take immediate action to prevent tobacco companies from illegally marketing new tobacco products in the United States without FDA authorization, including Altria’s on! PLUS nicotine pouch products. 

Currently, the FDA is also calling on nicotine pouch manufacturers to use child-resistant packaging due to rising reports of accidental exposure. Between 2020 and 2023, reported accidental ingestions of nicotine pouches by children younger than 6 years surged by approximately 763%

What are the health effects of oral nicotine pouches?

Is Zyn safe?

While specific long-term health effects of nicotine pouches like Zyn remain unknown, youth use of nicotine in any form is unsafe. Nicotine use during adolescence can disrupt the formation of brain circuits that control attention, learning, and susceptibility to addiction. Research has shown early age of nicotine use is correlated with daily use and lifetime nicotine dependence. Nicotine addiction can also intensify symptoms of depression and anxiety. 

Truth Initiative strongly urges the FDA to remove all unauthorized oral nicotine products from the market. To prevent youth from using these products, eliminating all flavors from tobacco products is crucial, as is instituting restrictions to curb exposure to marketing. 

Quitting Zyn and oral nicotine pouches

How to quit Zyn?

Quitting oral nicotine pouches like Zyn can be challenging, and the high levels of nicotine in these products can lead to nicotine addiction. The good news is, you can quit using oral nicotine pouches with similar strategies used to quit smoking and vaping. 

Read about how to quit Zyn and other oral nicotine pouches with EX Program, a digital quitting program developed by Truth Initiative with Mayo Clinic that can increase the odds of quitting by up to 40%.  

 

This article was originally published on May 23, 2023.

TAGS: Zyn